Spine Research

Osteoporosis, Fracture Healing and Teriparatide

The major concern about osteoporosis is the high risk of fracture that is often associated with decreased of the quality of life. Few drugs available for osteoporosis treatment may affect the bone repair, which can increase and accelerate fracture healing. Randomized studies and case reports show that Teriparatide, an anabolic agent, may have a positive impact on fracture healing, in both osteoporotic fractures and atypical femoral fractures. Other agents, such as strontium ranelate and anti-sclerostin also showed a benefit in bone repair. In spite of promising results with osteoporotic drugs in fracture healing, especially osteoanabolic agents, more randomized trials are required to whether approve or not the use of these drugs as a conservative and nom conservative therapy for osteoporotic fractures.

Author(s):

 João Lindolfo Cunha Borges and Isabela I Santiago

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