Immflamatory cascade was seen historically as detrimental CNS responses to injury that should be suppressed, however it is essential for tissue repair. Intraspinal inflammation caused by trauma persists indefinitely, becoming chronical. Chronical inflammation is detrimental for tissue regeneration. Treatments for spinal cord injury should resolve or modulate neuroinflammation at the appropriate time rather than suppress it completely.
Labombarda Florencia
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