The greatest risk factors for intervertebral disc degeneration are age, spinal level, excessive mechanical loading and genetic inheritance, a major cell-mediated change that occurs during degeneration is increased cell clustering. In fact, cell clusters formations are a histological hallmark behind intervertebral disc degeneration, yet a systematic review focusing on the cell clusters of the intervertebral disc is unknown. Therefore, the main purpose of this article is to discuss the role of cell cluster in intervertebral disc degeneration.
Polly Lama, Jyoti P Kulkarni and Binod K Tamang
All Published work is licensed under a Creative Commons Attribution 4.0 International License
Copyright © 2018 All rights reserved. iMedPub Last revised : January 22, 2018